Système immunitaire et cancer

Colloque organisé du 24 juin au 28 septembre 1985 par René Lefever et Jacques Urbain, à l’instigation du professeur Ilya Prigogine, le séminaire « Système immunitaire et cancer » a réuni des chimistes, des biologistes et des médecins.

Les interventions ont relevé de quatre thèmes principaux :

• Regulatory mechanisms in the immune system and growth control
• Cancer, immunity and metastasis,
• Cell mediated immune responses
• Manipulation of the anti-tumor immune response

Communications

• Paola Allavena (Instituto Mario Negri, Milan, Italy), Regulation and function of tumor infiltrating leucocytes
• Benjamin Bonavida (UCLA, Dept. of Microbiology and Immunology, USA), The role of soluble cytotoxic factors in cell mediated cytotoxicity
• Denis M. Callewaert (Oakland University, Dept. of Chemistry, USA), Kinetic analysis of natural cytotoxicity
• Jean-Charles Cerottini (Ludwig Institute for Cancer Research, Epalinges, Suisse), The function of cytotoxic T lymphocytes
• Klaus Eichmann (Max Planck Institute for Immunology, Freiburg, Germany), T cell repertoire
• Michael Feldman (Weizmann Institute of Sciences, Rehovot, Israel), Genes and antigens of metastasis
• Philip Frost (The University of Texas, Houston, USA), Tumor metastasis
• Pierre Golstein (CNRS, Centre d’Immunologie de Marseille Luminy, France), Mechanisms of cytotoxicity
• Mark I. Green (Tufts University School of Medicine, Boston, USA), The T lymphocyte suppressor cascade
• Karl Erik Hellström (University of Washington, Oncogene Corporation, Seattle, USA), Idiotypic manipulations of the anti-tumor response
• Thierry Hercend (Institut Gustave Roussy, Villejuif, France), Mechanisms of tumor cell recognition by human natural killer lymphocytes
• Jean Hiernaux (Université Libre de Bruxelles (ULB), Sce Chimie-Physique II, Belgique), Kinetic analysis of CTL clones
• Johan Hoebecke (Institut Jacques Monod, Paris VI)
• Dieter Kabelitz (University of Ulm, Germany), Induction of EBV specific MHC restricted human toxicity T cells
• René Lefever (Université Libre de Bruxelles (ULB), Belgique), Dynamical properties of cancer tissue attacked by immune cytotoxic cells
• Julia G. Levy (University of British Columbia, Vancouver, Canada), Role of T supressor lymphocytes in the anti-tumor response
• Jacqueline Marvel (Université Libre de Bruxelles (ULB), Belgique)
• Maria-Grazia Masucci (Karolinska Institute, Stockhom, Sweden), Oncogene activation and tumor immunity
• Patricia Meyers (Laboratoire de Physiologie animale, Rhode St-Genèse, Belgique)
• Aviron N. Mitchison (University College London (UCL), Dept. of Zoology), Immunoregulatory T lymphocytes
• Ilya Prigogine (1917-2003) (Université Libre de Bruxelles (ULB), Instituts Internationaux de Physique Chimie, Belgique), Opening remarks
• Patrick A. Riley (School of Medicine, University College London (UCL)), Melanocyte destruction initiated by tyrosine analogs as an approach to melano therapy
• John H. Russel (Washington University School of Medicine, St Louis, USA), Mechanisms of cytolysis
• Moncef Slaoui (Medical School Boston, USA)
• Dominique Stehelin (Institut Pasteur, Laboratoire d’Oncologie moléculaire, Paris), Viral and cellular oncogenes
• Jacques Urbain (Laboratoire de Physiologie animale, Rhode St-Genèse, Belgique), Idiotypic networks: order from the beginning or order out of chaos?
• Catherine Uyttenhove (Ludwig Institute for Cancer Research, Epalinges, Suisse), Enhancement of tumor immunity
• Frederick E. Wheelock (Hahnemann Medical College, Philadelphie, USA), Tumor dormance